Saturday, October 15, 2022

Advanced Abdominal Pregnancy

This blog post comprises of important points taken from the TOG article ‘Advanced abdominal pregnancy’ published in July 2022. It is strongly recommended to read the full article to have a complete understanding of this topic as this post is just a quick summary.


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Introduction

  • Abdominal pregnancy — when implantation occurs within abdominal cavity / an extra uterine pregnancy in which all or most of the foetus develops within the abdominal cavity
  • A rare form of ectopic pregnancy 
  • Incidence ~1% of all ectopic pregnancies
  • Associated maternal mortality  0-12% 
  • Overall risk of maternal death 7x that of ectopic pregnancy 90x that of an intrauterine pregnancy
  • Fetal survival >78%

Classification

Based on gestation at diagnosis

  • Early Abdominal Pregnancy (EAP) - before 20 weeks
  • Advanced Abdominal Pregnancy (AAP) - after 20 weeks

Based on site of implantation 

  • Primary abdominal pregnancy — implantation directly occurs in the abdominal cavity
  • Secondary abdominal pregnancy — when conception extruded from its primary site of implantation and re-implants in abdominal cavity (usually after ruptured ectopic)

Risk Factors

  • Most have no identifiable risk factors
  • Risk factors are same as any other ectopic pregnancy — tubal pathology, in situ IUCD, previous ectopic 
  • Uterine anomalies & history of previous uterine surgery (esp CS) are associated with abdominal pregnancy
  • AAP can also occur post scar rupture, previous myomectomy and post uterine perforation at surgical TOP, after IVF

Clinical Presentation

  • Diagnosis is often missed & usually made after fetal demise
  • Only 50% diagnosed before surgery
  • High suspicion is key to pre-operative diagnosis
  • No specific S&S of AAP


Symptoms 

  • Commonest presentation — abdominal pain ± vaginal bleeding (pain often persistent & increases by fetal movements)
  • Bloating & vomiting

Signs 

  • None pathognomonic
  • Reasonable sign of AAP - displaced cervix (anteriorly) 
  • Others— severe anaemia, abnormal fetal lie, oligohydramnios, SGA 

Ultrasound 

  • Abdominal pregnancy hard to diagnose with advancing gestation
  • Any first-trimester scan should include - location of gestational sac in relation to cervix, endometrial cavity and uterus
  • Intraabdominal pregnancy suspected on USG — extrauterine amniotic sac & an empty uterine cavity - foetus & placenta outside uterus, lack of uterine myometrium around foetus 
  • Skills & techniques of sonographer matters